While the verdict is still out on the benefits of probiotics, these supplements command a multibillion-dollar global market. Numerous clinical trials have aimed to determine the usefulness of probiotics, however, many have been hampered by limitations such as insufficient sample size. In this study, Freedman et al. investigate the efficacy of probiotics in the treatment of viral-induced pediatric acute gastroenteritis.
Highlights from the second iteration of the PRiME COVID-19 mini symposium established to showcase research recently funded by the Toronto COVID-19 Action Fund. This post features research being done to improve the throughput of SARS-CoV-2 testing, to develop robust antibody testing and therapeutics, and the facilities that support this expanding field.
The link between IBD and colon cancer is widely accepted. Irrazabal et al. establish a fascinating mechanistic link between these two devastating diseases. The pathobionts underlying IBD produce metabolites which lead to the increased production of reactive oxygen species, damaging the host DNA, and leading to tumorigenesis. Promisingly, the authors find that antioxidants can effectively treat this is mouse models.
The historic use of chlordecone as a pesticide to control banana weevil infestations has resulted in pollution of large land areas in the French West Indies. With a project spanning eight years, University of Toronto researchers provide evidence that bioremediation may be a viable approach to decontaminate chlordecone polluted grounds.
Throughout history, human travel has been heavily implicated in the spread of infectious disease. Increased connectivity via air travel can further facilitate the geographic spread of infectious diseases to vulnerable countries. Tuite and colleagues describe trends in international air passenger numbers and connectivity between countries with different capacities to detect and respond to infectious disease threats.