Using Antioxidants to Treat Bacterial-Induced Colorectal Cancer

The link between IBD and colon cancer is widely accepted. Irrazabal et al. establish a fascinating mechanistic link between these two devastating diseases. The pathobionts underlying IBD produce metabolites which lead to the increased production of reactive oxygen species, damaging the host DNA, and leading to tumorigenesis. Promisingly, the authors find that antioxidants can effectively treat this is mouse models.

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