New Perspective on Antiretroviral Treatments: Restricting HIV-1 Replication by Targeting Intracellular Signaling Pathways

Increased resistance to current antiretroviral therapies requires discovery of alternate measures for HIV treatment. Wong et al. identified 5342191 as a compound that restricts viral replication through activation of host intracellular signaling. Findings were replicated in both wild-type and HIV-resistant strains, making 5342191 a promising candidate for future treatments.

Continue ReadingNew Perspective on Antiretroviral Treatments: Restricting HIV-1 Replication by Targeting Intracellular Signaling Pathways