Host Microbe Interaction in Inflammatory Bowel Disesae - Mouse models of colitis and Large Human clinical and translational studies and Prospective Cohort Study of Subjects at Risk for IBD- The GEM Project

Selected publications:

1. Turpin W, Espin-Garcia O, Xu W, Silverberg MS, Kevans D, Smith MI, Guttman DS, Griffiths A, Panancionne R, Otley A, Xu L, Shestopaloff K, Moreno-Hagelsieb G, The GEM Project Research Consortium, Paterson AD, Croitoru K. Association of Host Genome with Intestinal Microbial Composition in a Large Healthy Cohort. Nature Genetics. 2016 Nov; 48(11):1413-1417.
2. Turpin, W., Bedrani, L., Espin-Garcia, O., Xu, W., Silverberg, M.S, Smith, M.I., Guttman, D., Griffiths, A., Moayyedi, P., Panaccione, R., Huynh, H., Steinhart, H., Aumais, G., Shestopaloff, K., Dieleman, L.A., Turner, D., CCC IBD GEM Project research team, Paterson, A.D., Croitoru, K. FUT2 genotype and secretory status are not associated with fecal microbial composition and inferred function in healthy subjects. Gut Microbes. 2018 Feb; 1-12.
3. Turpin,W, Goethel, A., Bedrani, L., Croitoru, K. Determinants of IBD heritability: genes, bugs and more. Inflammatory Bowel Diseases. 2018 March; 24(6): 1133-1148.
4. Goethel, A., Croitoru, K., & Philpott, D. The interplay between microbes and the immune response in inflammatory bowel disease. J Physiol. 2018 May 28. doi: 10.1113/JP275396.
5. Wang, J., Kurilshikov, A., Radjabzadeh, D., Turpin, W., Croitoru, K., & Bonder, M. Jackson, M., Medina-Gomez, C., Frost, F., Homuth, G., Rühlemann, M., Hughes, D., MiBioGen Consortium Initiative (2018), Timpson, N., Franke, A., Wijmenga, C., Meyer, K., Kacprowski, T., Franke, L., Paterson, A.D., Raes, J., Kraaij, R., Zhernakova, A. Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Microbiome. 8 June 2018: 6(1). doi: 10.1186/s40168-018-0479-3